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The Coronin Family of Proteins
Introduction.- Section I: The WD- and Kelch-Repeat Superfamilies. 1. Phylogenetic, Structural and Functional Relationships between WD and Kelch-Repeat Proteins. 2. Diversity of WD-Repeat Proteins.- Section II: History, Phylogeny, And Structure. 3. A Brief History of the Coronin Family. 4. Molecular Phylogeny and Evolution of the Coronin Gene Family. 5. Coronin Structure and Implications. Section III: Common And Diverse Functions. 6. Coronin: The Double-Edged Sword of Actin Dynamics. 7. Invertebrate Coronins. 8. Evolutionary and Functional Diversity of Coronin Proteins. 9. Role of Mammalian Coronin 7 in the Biosynthetic Pathway.- Section IV: Clinical Relevance. 10. Coronin 1 in Innate Immunity. 11. The Role of Mammalian Coronins in Development and Disease. Szczegóły